Cribbage is a game that the Eds are shown to play at Eddy's House when they're older. It's hinted that Eddy hates to play it, but plays it anyway. Ed states that cribbage gives him gas. They are seen playing it at the end of the Season 4 finale, "Take This Ed and Shove It."
Often, the Eds play it while reminiscing on their childhood memories, and Eddy seems to often fall asleep while doing this. The game involves playing and grouping cards in combinations to gain points on the board.